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  1. Home page | Molecular Cancer

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  2. Therapy-induced senescence is a transient drug resistance mechanism …

    May 1, 2025 · To further characterize the transcriptional changes and study the dynamics of TIS, as well as the molecular basis of potential resistance and escape mechanisms, we performed single-cell …

  3. Advances in cancer immunotherapy: historical perspectives, current ...

    May 7, 2025 · This review introduces key factors involved in cancer immunotherapy, including cancer vaccines, modified immune cells, and cytokines, while also exploring the combination of …

  4. Single-cell RNA sequencing identifies molecular biomarkers predicting ...

    Feb 15, 2025 · This study underscores the significance of molecular biomarkers in predicting clinical outcomes to CDK4/6i. Tumor-infiltration CD8+ T and NK cells may also serve as baseline predictors.

  5. Current AI technologies in cancer diagnostics and treatment

    Jun 2, 2025 · In order to learn more about the molecular basis of the disease, clinical oncology research has primarily focused on fully understanding the mechanisms driving the proliferation of cancer cells.

  6. Multi‑omics analysis identifies different molecular subtypes with ...

    May 1, 2025 · The emergence of cancer necessitates molecular alterations in both the transcriptome and epigenome. We further leveraged data from 78 patients who underwent both RNA-seq and …

  7. Inflammation in cancer: therapeutic opportunities from new insights

    Feb 24, 2025 · In this review, the detailed information on cytokines and their function in tumorigenesis are comprehensively analyzed, and their potential as therapeutic targets for cancer treatment and …

  8. Cancer, metastasis, and the epigenome - Molecular Cancer

    Aug 2, 2024 · The rising health and healthcare burden of cancer and the high toll of metastatic cancers create a correspondingly powerful incentive to understand their molecular pathophysiology.

  9. Immune dynamics shaping pre-metastatic and metastatic niches in …

    Nov 14, 2024 · Li Y, Li M, Su K, Zong S, Zhang H, Xiong L. Pre-metastatic niche: from revealing the molecular and cellular mechanisms to the clinical applications in breast cancer metastasis.

  10. Altered metabolism in cancer: insights into energy pathways and ...

    Sep 18, 2024 · Targeting glycolysis offers a promising avenue for cancer therapy, aiming to exploit the metabolic vulnerabilities of cancer cells. Several strategies are being explored, including inhibition of …