By setting up both reactions side by side in a test tube, the team revealed a literal tug-of-war between two DNA-repair pathways acting on the same HTT repeat. Which side wins likely determines ...
UniQure received FDA’s meeting minutes on AMT-130. While there were no new updates, the community’s response has been ...
Studies in mice that model Huntington’s disease suggest that prebiotics – the food that feeds our gut bacteria – might ...
As 2025 winds down, HD research is more active, more interdisciplinary, and more globally connected than ever. Whether it’s genetic modifiers, new drug targets, or next-generation clinical trials, ...
Piere studied Biology at Cayetano Heredia University in Lima (Peru), then obtained a PhD in Biophysics at UC Berkeley in the Bustamante Lab, specializing in molecular motors and single-molecule ...
Imagine a busy clothing factory. Proteins are like newly sewn shirts coming off the machines. They’re floppy, wrinkled, and can create a giant mess if they’re left unfolded. Normally, the cellular ...
SOM3355 is an investigational therapy aimed at managing multiple symptoms of Huntington’s disease (HD) and recently crossed two key regulatory milestones. In September, the European Medicines Agency ...
The one-year report from the TRACK-HD study demonstrates a number of changes in pre-symptomatic HD-mutation carriers ...
Scientists often use genetics, the study of DNA, to understand the cellular changes that cause disease. By comparing people’s DNA with their symptoms, they can pinpoint specific genetic differences, ...
Our bodies are experts at looking after our DNA and are continuously monitoring for any damage that needs to be repaired to keep us healthy. Parts of DNA that are very repetitive, like the sequence ...
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