When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

Cancer involves more than just genetic mutations; it also involves structural failures. Consider a city where roads disappear ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...