Anne van Schoonhoven is in the Departments of Pulmonary Medicine and of Cell Biology, Erasmus University Medical Center, Rotterdam 3015 GD, the Netherlands. Ralph Stadhouders is in the Departments of ...

Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the ...

A genomic analysis shows that transcription start sites are 35% more mutation-prone than expected, making them one of the ...

Deep beneath the ocean’s surface, where sunlight never reaches, a creature older than dinosaurs has quietly preserved secrets ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...

Through powerful high-resolution microscopy and precise biochemical methods, researchers at the Sloan Kettering Institute have seen for the first time how proteins and DNA come together to commence ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

CRISPR-Cas9 has been editing the human genome for the past decade. Although the types of edits have varied, an unsolved challenge has been the integration of large pieces of DNA without ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...