Until recently, the maturation of the 3′-end of tRNA precursors in Bacteria has been assumed to follow the E. coli paradigm, in which a cleavage event downstream of tRNAs is followed by exonucleolytic ...
A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...
In cells transfer RNA (tRNA) translates genetic information from the encoding messenger RNA (mRNA) for protein synthesis. New results from ultrafast spectroscopy and in-depth theoretical calculations ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 18 (May 3, 2016), pp. 4994-4999 (6 pages) During translation, a plethora of protein factors bind to the ...
Many viruses have genomes made of RNA. In human cells, messenger RNA (mRNA) molecules act as intermediates; cellular machinery copies a DNA sequence into mRNA so that it can then be translated into a ...
Aminoacyl-tRNA synthetases (aaRSs) are ancient and evolutionary conserved enzymes catalyzing the formation of aminoacyl-tRNAs, that are used as substrates for ribosomal protein biosynthesis. In ...
In an important, comprehensive, and timely review, an expert team from the University of California Berkeley details the methodologies used in nucleic acid-based tests for detecting the presence of ...
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