Cell growth and proliferation rates depend critically upon the rate of protein synthesis. Normal cells that are able to proliferate generally do so transiently in response to appropriate extracellular ...

Measuring translation initiation rates is difficult. Gao et al. developed quantitative translation initiation sequencing (QTI-seq), a technique that captures translation initiation sites (TISs) at ...

Cancer is the Houdini of diseases because it escapes elaborately contrived predicaments. Like Houdini, who was known to emerge triumphant after being handcuffed, locked in a trunk, and tossed into a ...

A team has recreated the harmful RAN translation process triggered by C9orf72 repeat expansions in ALS and FTD. Using a fully ...

ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Translational control plays an important role in cell growth and tumorigenesis. Cap-dependent translation initiation of mammalian mRNAs with structured 5' UTRs requires the DExH-box protein, DHX29, in ...

DNA translation is the term used to describe the process of protein synthesis by ribosomes in the cytoplasm or endoplasmic reticulum. The genetic information in DNA is used as a basis to create ...