Patients in 200 mg BID cohort had median progression free survival of 6.2 months and median overall survival of 28.1 months, comparing favorably ...
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Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing ...
Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor ...
A recent Science study explored how intranuclear metabolic enzymes establish the link between locus-specific epigenetic reprogramming of T cells and nutrient availability. Persistent antigen ...
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