The aim of this paper is to provide an overview of sample size estimations for the most frequent type of group studies that result in continuous, binary and ordered categorical outcomes. In recent ...

Choosing the proper sample size for an investigation is one of the crucial jobs required of a statistician. Regardless of whether the statistician is deciding the number of patients to select in a ...

The probability that the null hypothesis will be rejected when it is actually true is called the false positive rate and is determined by the significance level of the test (called alpha which is ...

Low statistical power undermines the purpose of scientific research; it reduces the chance of detecting a true effect. Perhaps less intuitively, low power also reduces the likelihood that a ...

Probability is a measure of the likelihood of events happening. The greater the proportion of times an event can happen the greater (or more likely) the probability. Events can be ordered by the ...

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...

When particles in a sample are the same size, one particle can be measured to report the result. If the sample has a narrow distribution, such as 10-25 µm, then measurement of just a few particles can ...