Alzheimer’s disease (AD) is a neurodegenerative condition in which amyloid plaques and neurofibrillary tangles accumulate in the brain. In addition to genetic factors, DNA damage and epigenetic ...

In the limited space of the nucleus, most of the genome is tightly folded, leaving accessible only the parts that need to be transcribed. There is “huge interest” in determining which elements of the ...

The next generation of a technique called ATAC-seq, which captures and sequences active regions of DNA (1), allows for the visualization of these regions as well. In ATAC-see, a so-called transposome ...

This is a preview. Log in through your library . Abstract Allopolyploidization, resulting in divergent genomes in the same cell, is believed to trigger a “genome shock”, leading to broad genetic and ...

Chinese researchers have developed a groundbreaking technology that sheds light on how the three-dimensional (3D) organization of plant genomes influences gene expression—especially in photosynthesis.