High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

Cell death triggered by GPX4 loss was slowed in cell cultures and in mouse model using compounds that specifically inhibit ferroptosis.

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the Institute of Science Tokyo reveal that a tandem allosteric effect of ...

A team from the University of Illinois has developed a modeling framework connecting enzyme activity related to photosynthesis to yield. This is the first time a model has tied the dynamic ...

The inhibition of an enzyme associated with neurodegeneration processes reduced the toxic effect of tau, one of the proteins that damage neurons in Alzheimer’s disease (AD). A group of scientists from ...

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ...

Nicotiana benthamiana plants in a lab at UC Davis. Plants form new branches when a hormone called strigolactone breaks down. UC Davis plant biologists have now defined the enzymes that break down ...

Researchers from Stanford University have reported that inhibiting the enzyme 15-hydroxyprostaglandin dehydrogenase (15-PGDH) ...

Researchers from the Cluster of Excellence Balance of the Microverse at the University of Jena and the Leibniz-HKI, together ...

Alternating non-cross-resistant multiagent chemotherapy (ANCRC) and high-dose chemotherapy followed by autologous stem cell support (HDC-ASCS) in first remission to improve outcome in patients with ...